The 161st Notice of AgriX Forum | Big Data Breeding Reform in the Post genomic Era
In the last Baibo Wisdom Lecture Hall, Qu Mingnan, a researcher from Yazhou Bay Seed Laboratory in Hainan Province, was invited to share the content of "Building and Application of High Light Efficiency Digital Crop Phenotype Platform". The lecture was very exciting, and you are welcome to watch the replay.
This is the 161st issue of Baibo Wisdom Lecture Hall (August 18). Researcher Xia Zhiqiang, Vice Dean of Tropical Crops College of Hainan University, was invited to share the content of "big data breeding reform in the post genomic era". Welcome to this lecture!
Vice President of Tropical Crops College of Hainan University——Researcher Xia Zhiqiang
The 161st Lecture
Xia Zhiqiang, a researcher, doctoral supervisor, a visiting scholar at the University of California, Davis, USA, a young celebrity in the South China Sea of Hainan Province, and a vice president of the Tropical Crops College of Hainan University. Develop a multi-dimensional omics platform to provide big data analysis systems such as complex genomes and methylation at the chromosome level. The first fine genome map of cassava, passion fruit, acorn, canna taro and canna was published. It has originally developed two generations of ultra low-cost genotyping technology Hyper seq and epigenetic analysis technology AFSM, which have been successfully used in the research of more than 10000 samples of about 50 species, and has won 4 national invention patents and 3 international invention patents. He has published influential academic papers in SCI journals such as The Innovation, Plant Biotechnology Journal, Nuclear Acids Research, Horticulture Research, Molecular Ecology Resources, Biotechnol Biofuels, Nature Communications, etc., including 26 first authors or correspondents. The cumulative impact factor exceeds 150. Perennial reviewers of Horticulture Research, Biotechnol Biofuels and other journals, and deputy chief editor of Tropical Plants. Served as the special director of two national key R&D projects, presided over and participated in more than 10 scientific research projects such as the National Natural Science Foundation of China, the Key Fund, the 973 Program of the Ministry of Science and Technology, and the national cassava industry system.
Targeted sequencing is a method to isolate, enrich and sequence a group of target genes or genome regions. This method enables researchers to focus time, cost and data analysis on specific regions of interest (target regions, genes), and use less data to obtain higher sensitivity and accuracy, so as to achieve rapid screening of mutation sites. These target regions usually include exome (the protein coding part of the genome), specific genes of interest (customized content), and target regions in genes or mitochondrial DNA.
FBI seq (Foreground and Background Integrated genotyping by sequencing) is not sequencing by the US Federal Bureau of Investigation, but genotyping sequencing integrating foreground and background. As the name implies, this technology realizes the detection and selection of foreground genes and genetic background at the same time. The selection of foreground and background is two very important steps in molecular breeding. At present, breeders often need to carry out these two steps independently: first, screen foreground target sites, and then develop a large number of probes/bait/PCR primers to detect background genotypes. These time-consuming and costly preparations greatly delay the start of breeding projects.
Deeply cultivate the agricultural core, and work together for the future. In response to the call of the country to build a "China core" of seed industry, and to promote the joint construction of the "Northern Seed City", Phoenix Expo was officially upgraded to the "China Northern Seed Expo" on the basis of successfully holding three sessions of China Shandong International Vegetable Seed Expo, focusing on new varieties and new technologies such as field, vegetables, fruits and vegetables, horticulture, balcony agriculture, and combining cloud seed industry, cloud plant protection, cloud agricultural science platform, Build online and offline promotion and trading dual platforms for seed breeding. The 2022 Northern Species Expo will be linked with the 29th Shandong Double Trade Fair for Plant Protection, China Shandong International New Fertilizer Exhibition, and China (Shandong) New Agricultural Equipment Exhibition!